Current research at ReMind UK

We are delivering a range of clinical trials and non-drug studies to test treatments and improve outcomes for people affected by dementia and other conditions

Alzheimer's disease research

MSD Trial in Early Alzheimer’s

Researchers want to know if the study treatment works to slow certain changes in the brains of people with Alzheimer’s disease. It is a phase 2 study treatment for people with early Alzheimer’s disease. To take part in the study particpants must:

  • Be between 50 and 85 years old
  • Have mild cognitive impairment (MCI) or mild dementia due to Alzheimer’s disease

Dementia disease & mild cognitive impairment research

This study, run by the University of Oxford, is looking for participants aged 45 years and older who have either been diagnosed with dementia or Mild Cognitive Impairment or have presented to a clinician with memory complaints but have no specific diagnosis. You will be invited to the ReMind UK Clinic to give a single blood sample of 20 mL (roughly the same as 1.5 tablespoons), answer some questions about your medical history and demographics and complete a questionnaire about your feelings toward dementia diagnosis and whether blood tests may be a useful tool for your medical care.

Trontier

Trontier is a nineteen month phase three trial for people diagnosed with mild cognitive impairment or mild Alzheimer’s disease. Participants take either trontinemab, a monoclonal
antibody targeting the brain, or a placebo to test the effectiveness and safety
of the drug.

Dementia carers research

CareCoach is an online support package which focuses on helping caregivers develop knowledge, skills, and confidence to manage and support the care they provide a person living with dementia. Care givers using CareCoach are also supported and guided by a ‘coach’ (health, social care or dementia charity worker).

Read John’s story and experience as a participant of CareCoach

Other research studies

The Fastball study involves showing a person some pictures to remember and then showing the pictures to them at a very fast rate, mixed up amongst pictures they have not seen. Using Electroencephalography (EEG), which measures brain activity using easy-to-use headsets, it’s possible to see brain waves from areas of the brain that recognise images, to show whether the person remembers the pictures or not. The Research Team – led by the Department of Psychology at the University of Bath, in partnership with the University of Bristol, University College London (UCL), Cumulus Neuroscience Ltd., and the North Bristol NHS Trust – has already shown that Fastball can detect the early stages of dementia, and it works whatever language the person speaks, how educated or nervous they are. Fastball is now being used in dementia clinics in Bristol and Bath to see if dementia can be diagnosed earlier and more accurately than with pen and paper tests.

Volunteer for dementia research

We believe people diagnosed with dementia should be given the opportunity to participate in research trials whenever possible.  We also manage a list of ‘Healthy Brain volunteers’ who do not have a dementia diagnosis. Contact us with your details to join our Research Register. There are no obligations to take part but we might contact you to discuss any opportunities that should arise. To find out more contact our Research Manager: research@reminduk.org

Read about why Alexander chose to take part in dementia research.

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