Current research at ReMind UK
We are delivering a range of clinical trials and non-drug studies to test treatments and improve outcomes for people affected by dementia and other conditions
Alzheimer's disease research
This study, run by the University of Oxford, is looking for participants aged 45 years and older who have either been diagnosed with dementia or Mild Cognitive Impairment or have presented to a clinician with memory complaints but have no specific diagnosis. You will be invited to the ReMind UK Clinic to give a single blood sample of 20 mL (roughly the same as 1.5 tablespoons), answer some questions about your medical history and demographics and complete a questionnaire about your feelings toward dementia diagnosis and whether blood tests may be a useful tool for your medical care.
The ReTain clinical research study is for adults who are concerned about their risk of developing Alzheimer’s disease. Participants must be currently healthy with no cognitive impairment. The trial will assess the effect of an immunotherapy medication on cognitive decline, this medication will be given by injection to the upper arm.
Trontier
Trontier is a nineteen month phase three trial for people diagnosed with mild cognitive impairment or mild Alzheimer’s disease. Participants take either trontinemab, a monoclonal
antibody targeting the brain, or a placebo to test the effectiveness and safety
of the drug.
MSD trial in Mild to Moderate Alzheimer’s
This trial, run by MSD, is testing whether the addition of a tablet combined with other dementia medication is effective in delaying memory loss and thinking problems in people with a diagnosis of mild to moderate Alzheimer’s disease.
MSD trial in Early Alzheimer’s
This trial, run by MSD, is a phase 2 clinical trial for those with early Alzheimer’s disease aged 50 to 85 years old. The study which opens this autumn, aims to determine the safety of a drug and test how it compares to placebo in the treatment of Alzheimer’s disease.
Dementia carers research
CareCoach is an online support package which focuses on helping caregivers develop knowledge, skills, and confidence to manage and support the care they provide a person living with dementia. Care givers using CareCoach are also supported and guided by a ‘coach’ (health, social care or dementia charity worker).
A questionnaire exploring the experiences of Indian-British dementia caregivers in the UK. This research will assess the wellbeing and stress levels of carers who look after someone living with dementia. By taking part, you will be entered into a prize draw for a £50 voucher.
Other research studies
The Fastball study involves showing a person some pictures to remember and then showing the pictures to them at a very fast rate, mixed up amongst pictures they have not seen. Using Electroencephalography (EEG), which measures brain activity using easy-to-use headsets, it’s possible to see brain waves from areas of the brain that recognise images, to show whether the person remembers the pictures or not. The Research Team – led by the Department of Psychology at the University of Bath, in partnership with the University of Bristol, University College London (UCL), Cumulus Neuroscience Ltd., and the North Bristol NHS Trust – has already shown that Fastball can detect the early stages of dementia, and it works whatever language the person speaks, how educated or nervous they are. Fastball is now being used in dementia clinics in Bristol and Bath to see if dementia can be diagnosed earlier and more accurately than with pen and paper tests.
Liv Dem Families
We are looking for healthy volunteers (no dementia diagnosis) to help out as a control group for a study of a non-invasive test to diagnose dementia. This test, called ‘Fastball’ measures brain waves while showing someone images displayed on a screen. Early evidence suggests that the test is effective in picking up on subtle changes in the brain.
Volunteer for dementia research
We believe people diagnosed with dementia should be given the opportunity to participate in research trials whenever possible. We also manage a list of ‘Healthy Brain volunteers’ who do not have a dementia diagnosis. Contact us with your details to join our Research Register. There are no obligations to take part but we might contact you to discuss any opportunities that should arise. To find out more contact our Research Manager: vanessa.bishop@reminduk.org
Read about why Roger chose to take part in dementia research.